Stabilized topical acidic fibroblast growth factor formulation

A - Human Necessities – 61 – K

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Details

A61K 38/18 (2006.01) A61K 47/18 (2006.01) A61K 47/36 (2006.01) A61K 47/38 (2006.01) A61L 26/00 (2006.01)

Patent

CA 2080537

JLT31 18554 TITLE OF THE INVENTION STABILIZED TOPICAL ACIDIC FIBROBLAST GROWTH FACTOR FORMULATION ABSTRACT THE INVENTION A sterile aqueous medicinal composition containing acidic fibroblast growth factor combined with an amount of heparin sufficient to stabilize acidic fibroblast growth factor, with said acidic fibroblast growth factor and heparin combined with a sufficient amount of hydroxyethyl cellulose to form a viscous solution which when dried forms a film, with said acidic fibroblast growth factor, heparin and hydroxyethyl cellulose combined with a chelating agent capable of stabilizing the composition at temperatures higher that 4° C.

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