Stabilized transdermal drug delivery system

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/70 (2006.01) A61M 35/00 (2006.01)

Patent

CA 2726136

A solid dispersion transdermal drug delivery system comprising a therapeutic agent in a stable amorphous form and a combination polymeric stabilizing and dispersing agent having a hydrogen bond-forming functional group, and a method of manufacturing these systems is provided. The weight ratio of the combination polymeric stabilizing and dispersing agent to the therapeutic agent is also disclosed.

La présente invention concerne un système dadministration de médicament transdermique en dispersion solide comprenant un agent thérapeutique sous une forme amorphe stable et un agent stabilisant et dispersant polymère combiné ayant un groupe fonctionnel formant des liaisons hydrogène, et un procédé de fabrication de ces systèmes. La présente invention concerne en outre le rapport en poids de lagent stabilisant et dispersant polymère combiné à lagent thérapeutique.

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