Stabilized vitamin d preparation

Details Stabilized vitamin d preparation Stabilized vitamin d preparation

A - Human Necessities

61

K

A61K 31/59 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01)

Patent

CA 2065603

The present invention provides a pharmaceutical composition of a heat-labile vitamin D active compound dispersed in a basic polymer; a pharmaceutical composition, which comprises an excipient readily soluble in an organic solvent, a heat-labile vitamin D2 active compound,and a basic substance; or a pharmaceutical composition, which comprises homogeneous dispersion of a finely pulverized heat-labile vitamin D active compound in a basic substance and an excipient readily soluble in water. In the composition of this invention, thermal. isomerization, decomposition and discoloration is remarkably reduced, keeping excellent stability.

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