A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/25 (2006.01) A61K 9/00 (2006.01) A61K 39/12 (2006.01) A61K 39/165 (2006.01) A61K 39/20 (2006.01) A61K 47/42 (2006.01) A61K 47/02 (2006.01) A61K 47/18 (2006.01) A61K 47/26 (2006.01)
Patent
CA 2302282
Compositions are provided for improving the stability of live virus vaccines containing, e.g., live varicella zoster, measles, mumps, and rubella viruses. Such improved stabilizers are aqueous solutions containing recombinant human serum albumin (rHA) as a component at from 1-100 g/l. Live virus vaccines as well as methods of preparing live virus vaccines containing the stabilizers are also provided.
L'invention porte sur des compositions améliorant la stabilité de vaccins de virus vivants, par exemple de la varicelle-zona, des oreillons, de la parotidite ou de la rubéole. Ces stabilisateurs améliorés consistent en solutions aqueuses dont l'un des composants est de l'albumine sérique humaine de recombinaison (rHA) à raison de 1 à 100 g/l. L'invention porte également sur les vaccins de virus vivants contenant lesdits stabilisateurs ainsi que sur leurs procédés de préparation.
Burke Carl
Volkin David
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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