C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/00 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) C12N 1/04 (2006.01) C12N 7/01 (2006.01) C12N 15/86 (2006.01)
Patent
CA 2630349
This invention relates to preparations of viruses, e.g. for vaccine or other pharmaceutical or research use, to their stabilization, and to processes of producing such preparations, as well as to their use, e.g. as vaccines or as virus vectors. The formulations comprise a sugar, a preservative, a dispersing agent, a thermal stability agent, a buffer, and up to three distinct types of amino acids without impacting the structural appearance of the lyophilized product.
L'invention concerne des préparations de virus, par ex., pour un vaccin ou d'autres applications pharmaceutiques ou de recherches, leur stabilisation et des procédés pour produire des préparations de ce type, ainsi que leur utilisation, par ex., en tant que vaccins ou vecteurs de virus. Ces formulations comprennent un sucre, un agent de conservation, un agent de dispersion, un agent de stabilité thermique, un tampon et jusqu'à trois types différents d'acides aminés sans impact sur l'apparence structurelle du produit lyophilisé.
Sanofi Pasteur Limited
Yacoob Reza K.
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