C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/00 (2006.01) G01N 33/487 (2006.01)
Patent
CA 2600132
A reagent composition containing GDH-PQQ as an enzyme-co-factor and screen- printed on working and counter electrodes of electrochemical biosensors, maintains activity of the enzyme reagents by proper selection of components. A preferred composition includes hydrophilic polymers, amorphous untreated silica, buffers, surfactants, and a mediator. For example, the biosensor is useful in the amperometric determination of glucose.
La présente invention concerne une composition réactive contenant du GDH-PQQ servant de cofacteur d'enzyme. Cette composition sérigraphiée sur les électrodes directes et les contre-électrodes de biocapteurs électrochimiques, entretient l'activité des réactifs enzymatiques par une sélection appropriée des composants. Une composition préférée contient des polymères hydrophiles, de la silice amorphe non traitée, des tampons, des tensioactifs, et un médiateur.
Chu Amy H.
Spradlin Hope G.
Bayer Healthcare Llc
Osler Hoskin & Harcourt Llp
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