A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/22 (2006.01)
Patent
CA 2528988
The present invention provides an aqueous formulation of human erythropoietin having the storage stability over a long period without serum albumin, in which the formulation comprises a pharmaceutically effective amount of human erythropoietin; non-ionic, polyhydric alcohol, neutral amino acid and sugar alcohol as stabilizers; isotonic reagent; and buffering reagent.
La présente invention concerne une préparation aqueuse d'érythropoïétine humaine possédant une stabilité de stockage sur le long terme et ne contenant pas d'albumine sérique. Cette préparation comprend une quantité pharmaceutiquement efficace d'érythropoïétine humaine, un tensioactif non ionique, un alcool polyhydrique, un acide aminé neutre et un alcool de sucre comme stabilisants, un réactif isotonique et un réactif tampon.
Choi Suk Young
Jeh Hoon Sung
Kang Young Cheol
Kim Ji Eon
Kim Myung Jin
Gowling Lafleur Henderson Llp
Lg Life Sciences Ltd.
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