Stable bicarbonate ion-containing drug solution

Details Stable bicarbonate ion-containing drug solution Stable bicarbonate ion-containing drug solution

A - Human Necessities

61

K

A61K 33/42 (2006.01) A61K 31/7004 (2006.01) A61K 33/10 (2006.01) A61K 33/14 (2006.01) A61P 7/08 (2006.01)

Patent

CA 2701249

The invention relates to a stable bicarbonate ion-containing drug solution, particularly a bicarbonate-containing drug solution for dialysis in which the stability has been improved by the presence of a phosphate ion. Further, the invention relates to a drug solution for acute blood purification, particularly a dialysate and a substitution liquid for acute blood purification to be mixed before use containing the drug solution. Still further, the invention relates to a dialysate and a substitution liquid for acute blood purification to be mixed before use in which the formation of insoluble fine particles or precipitates is prevented for a long time after mixing and with which hypokalemeia and hypophosphatemia are not caused.

La présente invention concerne une solution médicamenteuse stable renfermant l'ion bicarbonate, en particulier une solution médicamenteuse contenant du bicarbonate pour dialyse dans laquelle la stabilité a été améliorée par la présence d'un ion phosphate. En outre, l'invention concerne une solution médicamenteuse pour une purification aiguë du sang, en particulier un dialysat et un liquide de substitution pour purification aiguë du sang à mélanger avant utilisation contenant la solution médicamenteuse. Et en outre, l'invention concerne un dialysat et un liquide de substitution pour une purification aiguë du sang à mélanger avant utilisation, dans lequel la formation de fines particules ou de précipités insolubles est empêchée pendant une longue période après le mélange et avec lequel il n'est provoqué aucune hypokaliémie et hypophosphatémie.

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