Stable cannabinoid compositions comprising crystalline...

A - Human Necessities – 61 – K

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A61K 31/352 (2006.01) A61P 1/08 (2006.01) A61P 29/02 (2006.01)

Patent

CA 2612061

Pharmaceutical compositions comprising the cannabinoid active pharmaceutical ingredient, crystalline trans-(~)-.DELTA.9-tetrahydrocannabinol, and formulations thereof are disclosed. The invention also relates to methods for treating or preventing a condition such as pain comprising administering to a patient in need thereof an effective amount of crystalline trans-(~)-.DELTA.9- tetrahydrocannabinol. In specific embodiments, the crystalline trans-(~)- .DELTA.9-tetrahydrocannabinol administered according to the methods for treating or preventing a condition such as pain can have a purity of at least about 98% based on the total weight of cannabinoids.

L'invention concerne des compositions pharmaceutiques comprenant un ingrédient pharmaceutique actif à base de cannabinoïdes, le trans-(±)-?9-tétrahydrocannabinol cristallin, ainsi que des préparations correspondantes. L'invention concerne également des méthodes destinées à traiter ou prévenir une affection telle que la douleur et consistant à administrer, à un patient le nécessitant, une dose efficace d'un trans-(±)-?9-tétrahydrocannabinol cristallin. Dans des modes de réalisation spécifiques, le trans-(±)-?9-tétrahydrocannabinol cristallin utilisé dans les méthodes de traitement ou de prévention d'une affection telle que la douleur peut présenter une pureté d'au moins environ 98% sur la base du poids total des cannabinoïdes.

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