Stable composition comprising particles in a frozen aqueous...

Details Stable composition comprising particles in a frozen aqueous... Stable composition comprising particles in a frozen aqueous...

A - Human Necessities

61

K

A61K 9/10 (2006.01) A61K 8/02 (2006.01) A61K 9/14 (2006.01) A61K 31/12 (2006.01) A61K 31/4985 (2006.01) A61K 31/58 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2463313

The present invention discloses a composition of a stable suspension of a poorly water soluble pharmaceutical agent or cosmetic in the form of particles of the pharmaceutical agent or cosmetic suspended in a frozen aqueous matrix and method for its preparation. The composition is stable for a prolonged period of time, preferably six months or longer and is suitable for parenteral, oral, or non-oral routes such as pulmonary (inhalation), ophthalmic, or topical administration.

La présente invention concerne une composition formée d'une suspension stable d'un agent pharmaceutique ou cosmétique, faiblement soluble dans l'eau, se présentant sous forme de particules de cet agent pharmaceutique ou cosmétique qui sont en suspension dans une matrice aqueuse gelée et un procédé de préparation de cette dernière. La composition est stable sur une durée étendue, qui est de préférence égale ou supérieure à six mois et appropriée pour l'administration par voie parentérale, orale ou non orale telle que la voie pulmonaire (inhalation), ophtalmique ou topique.

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