Stable copper (i) complexes and their use as active...

A - Human Necessities – 61 – K

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A61K 31/555 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2163640

There is disclosed stable copper (I) complexes and methods relating thereto. The stable copper(I) complexes comprise a copper (I) ion complexed by a multi-dentate ligand which favors the +1 oxidation state for copper. Methods of this invention include the use of the stable copper (I) complexes as wound healing agents, anti-oxidative agents, anti-inflammatory agents, lipid modulating agents, signal transduction modulating agents, hair growth agents, and anti-viral agents. Exemplary stable copper (I) complexes include neocuproine copper (I) and bathocuproine disulfonic acid copper (I).

L'invention concerne des composés stables de cuivre(I) et des procédés affins. Les composés stables de cuivre (I) comprennent un ion de cuivre(I) associé à un ligand polydenté qui favorise l'état de d'oxydation +1 du cuivre. Les procédés décrits comprennent l'utilisation des composés stables de cuivre(I) comme agents de guérison de blessures, agents antioxydants, agents anti-inflammatoires, modulateurs de lipides, modulateurs de la transduction de signaux, comme agents stimulant la pousse des cheveux et comme agents antiviraux. Des exemples de composés stables de cuivre(I) comprennent la néocupréine de cuivre(I) et l'acide disulfonique de bathocuproïne de cuivre(I).

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