Stable corticosteroid mixtures

Details Stable corticosteroid mixtures Stable corticosteroid mixtures

A - Human Necessities

61

K

A61K 9/12 (2006.01) A61K 31/56 (2006.01)

Patent

CA 2642641

A corticosteroid mixture, such as a budesonide solution, is prepared by the active and inactive ingredients of the mixture under oxygen-depleted conditions. The resulting mixture demonstrates superior stability of the activ pharmaceutical ingredient corticosteroid. The invention provides novel methods of manufacturing corticosteroid mixtures, wherein the resulting mixtures possess superior stability as compared to known methods.

L'invention concerne un mélange corticostéroïde, tel qu'une solution de budésonide, préparé à partir d'ingrédients actifs et inactifs du mélange sous des conditions de déplétion en oxygène. Le mélange résultant présente une stabilité supérieure de l'ingrédient corticostéroïde pharmaceutiquement actif. L'invention concerne de nouvelles méthodes pour fabriquer des mélanges corticostéroïdes, les mélanges résultants possédant une stabilité supérieure à celle de méthodes connues.

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