A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 8/365 (2006.01) A61K 8/06 (2006.01) A61K 8/67 (2006.01) A61Q 19/00 (2006.01) A61Q 19/08 (2006.01)
Patent
CA 2304122
The inventive compositions contain an oil-in-water and a water-in-oil emulsion, each buffered to a specific pH, so that the difference in pH values of the two emulsions is at least two units. The molecular mixing is minimized by selecting suitable oil and oil phase in a water-in-oil emulsion. The change in pH is further minimized by buffering each emulsion. The particular advantage of the inventive compositions is the ability to separate within a single composition, with minimal intermixing, active compounds which require different pH environments for stability and/or optimum efficacy.
L'invention concerne des compositions renfermant une émulsion huile-dans-eau et eau-dans-huile, chacune tamponnée à un pH spécifique de manière que la différence des valeurs pH des deux émulsions soit d'au moins deux unités. On réduit le mélange moléculaire en sélectionnant de manière adéquate l'huile et la phase huileuse dans une émulsion eau-dans-huile. On réduit ensuite la variation de pH en tamponnant chaque émulsion. Cette composition convient particulièrement lorsque l'on souhaite séparer dans une seule composition, avec un mélange minimum, des composés actifs nécessitant différents environnements pH en vue d'une stabilité de stockage et/ou d'une efficacité optimale.
Habif Stephen Samuel
Mukherjee Surajit
Rick Donald
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Plc Unilever
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