Stable cytochrome p450 24 (cyp24) expressing cell line and...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 5/10 (2006.01) C12N 9/02 (2006.01) C12N 15/53 (2006.01)

Patent

CA 2484244

The invention relates to a stable recombinant host cell comprising a CYP24 nucleic acid. The host cell is preferably a mammalian cell or an insect cell. The cell is useful for identifying modulators of CYP24 that can be used in the treatment of CYP24 expression - related medical conditions.

L'invention concerne une cellule hôte de recombinaison stable renfermant un acide nucléique CYP24. De préférence, la cellule hôte est une cellule mammalienne ou une cellule d'insecte. Il s'agit d'une cellule utile pour l'identification de modulateurs de CYP24 susceptibles d'être utilisés dans le traitement d'états pathologiques liés à l'expression de CYP24.

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