Stable elsamitrucin salts suitable for pharmaceutical...

C - Chemistry – Metallurgy – 07 – H

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C07H 15/24 (2006.01) A61K 31/7048 (2006.01) A61P 35/00 (2006.01) C07H 17/04 (2006.01)

Patent

CA 2654877

Stable solid, crystalline forms of elsamitrucin salts are provided that are useful in preparing anti-neoplastic parenteral formulations. Also provided are methods for treating neoplastic diseases in humans using parenteral formulations that include at least one stable elsamitrucin salt.

L'invention porte sur des formes cristallines, solides, stables, de sels d'elsamitrucine, qui sont utiles dans la préparation de formulations parentérales antinéoplasiques. L'invention porte également sur des procédés pour traiter des maladies néoplasiques dans des êtres humains utilisant des formulations parentérales qui comprennent au moins un sel d'elsamitrucine stable.

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