Stable extended release oral dosage composition

Details Stable extended release oral dosage composition Stable extended release oral dosage composition

A - Human Necessities

61

K

A61K 31/135 (2006.01) A61K 9/24 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2147606

A film-coated extended release oral dosage composition containing the nasal decongestant pseudoephedrine or salt there-of, e.g., pseudoephedrine sulfate in a unique polymer matrix core and a film-coating on such core containing the non-sedating antihistamine, loratadine, and use of the said composition for treating patients showing the signs and symptoms associated with upper respiratory diseases and nasal congestion are disclosed.

L'invention concerne une composition de dose administrée oralement, à libération prolongée, revêtue d'un film, contenant de la pseudoéphédrine, qui est un décongestif nasal, ou bien un sel de celle-ci, par exemple du sulfate de pseudoéphédrine dans un noyau matriciel en polymère unique et un film recouvrant ledit noyau et contenant de la loratadine qui est un antihistaminique non sédatif. L'invention concerne également l'utilisation de ladite composition pour traiter des patients présentant les signes et les symptômes associés aux maladies des voies respiratoires supérieures et à la congestion nasale.

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