Stable formulation of analapril salt, a process for the...

Details Stable formulation of analapril salt, a process for the... Stable formulation of analapril salt, a process for the...

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 9/20 (2006.01) A61K 38/55 (2006.01)

Patent

CA 2083683

There is disclosed a stable formulation of enalapril salt of the formula I (see formula I) which is prepared in such manner that a compound of formula II (see formula II) is suspended in demineralized water and a stoichiometric amount of the corresponding sodium compound such as sodium carbonate, sodium hydrogen carbonate or sodium hydroxide is added thereto, to this enalapril sodium salt prepared in situ of the formula I (see formula III) formulating additives are added, the whole is homogenized and formulated.

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