Stable freeze-dried formulation comprising a protein; assay kit

A - Human Necessities – 61 – K

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Details

A61K 47/26 (2006.01) A61K 9/19 (2006.01) A61K 38/20 (2006.01) A61K 38/27 (2006.01) A61K 38/44 (2006.01) A61K 47/00 (2006.01) A61K 47/18 (2006.01) G01N 33/531 (2006.01)

Patent

CA 2148537

The subject of the invention is a formulation which is stable, freeze-dried and pharmaceutically acceptable, comprising a protein, a buffer, alanine and mannitol, in which the ratio R = mass of mannitol/mass of alanine is between 0.1 and 1. The protein is especially a protein with biologi- cal activity such as a hormone, in particular hGH, an enzyme or a cytoking. The subject of the invention is also an assay kit comprising a formulation previously defined.

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