Stable high-concentration injection containing pyrazolone...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/4152 (2006.01) A61K 9/08 (2006.01) A61K 47/10 (2006.01) A61K 47/18 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) C07D 231/20 (2006.01)

Patent

CA 2446837

An injection which contains as the active ingredient a pyrazolone derivative which typically is Edaravone, a physiologically acceptable salt thereof, or a hydrate or solvate of either in an amount of 3 to 60 mg/mL. It is excellent in long-term stability, product storage, and suitability for use.

L'invention concerne un produit d'injection qui contient, comme principe actif, un dérivé de pyrazolone (qui est généralement edaravon), un sel physiologiquement acceptable dudit dérivé, ou un hydrate ou un solvate de l'un ou l'autre, selon une quantité comprise entre 3 et 60 mg/ml. Ce produit d'injection présente d'excellentes qualités de stabilité à long terme, d'entreposage, et d'adéquation.

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