Stable immunogenic product comprising antigenic heterocomplexes

Details Stable immunogenic product comprising antigenic heterocomplexes Stable immunogenic product comprising antigenic heterocomplexes

A - Human Necessities

61

K

A61K 39/385 (2006.01) A61P 37/04 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2499214

The invention relates to a stable immunogenic product for the induction of antibodies against one or more antigenic proteins in a subject. The invention is characterised in that it comprises proteinaceous immunogenic heterocomplexes which are formed by associations between (i) antigenic protein molecules and (ii) proteinaceous carrier molecules and in that less than 40 % of the antigenic proteins (i) are linked to the proteinaceous carrier molecules (ii) by a covalent bond.

L'invention se rapporte à un produit immunogène stable pour l'induction d'anticorps à; l'encontre d'une ou plusieurs protéines antigéniques chez un sujet , caractérisé en ce qu'il comprend des hétérocomplexes immunogènes protéiques constitués d'associations entre (i) des molécules de protéines antigéniques et (ii) des molécules protéiques porteuses et en ce que moins de 40 pour cent des protéines antigéniques (i) sont liées aux molécules protéiques porteuses (ii) par une liaison covalente.

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