Stable injectable pharmaceutical formulation for folic acid...

Details Stable injectable pharmaceutical formulation for folic acid... Stable injectable pharmaceutical formulation for folic acid...

A - Human Necessities

61

K

167/219

A61K 47/20 (2006.01) A61K 31/505 (2006.01) A61K 47/00 (2006.01)

Patent

CA 2023563

Injectable aqueous compositions comprising folic acid and leucovorin and their salts, optionally including benzyl alcohol, sodium chloride and agents for adjusting pH are stabilized and buffered in the range of 6 to 10 by adding a combination of tromethamine and monothioglycerol. Such compositions remain stable for prolonged periods even when exposed to sunlight:

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