A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 24/06 (2006.01) A61B 17/08 (2006.01) A61F 13/02 (2006.01) A61L 15/58 (2006.01) A61L 24/00 (2006.01)
Patent
CA 2453620
The present invention provides medicament-containing cyanoacrylate adhesive formulations for sealing wounds. The adhesive comprises a cyanoacrylate, a substance, and a defect forming agent, wherein the defect forming agent is capable of being removed from a cured cyanoacrylate matrix by solvation in an aqueous solution whereby a plurality of defects in the matrix are formed permitting release of the substance from the matrix at a controlled rate.
La présente invention concerne des formulations d'adhésif à base de cyanoacrylate renfermant un médicament cicatrisant. L'adhésif renferme un cyanoacrylate, une substance et un agent porogène. Cet agent porogène peut être retiré d'une matrice de cyanoacrylate durcie par solvatation d'une solution aqueuse dissolvante. La pluralité de pores formés dans la matrice assure une libération contrôlée de la substance hors de la matrice.
Dickson Cindy
Gu Min Di
Kirsch Wolff M.
Shen Qun-Dong
Yang Chang Zheng
Fetherstonhaugh & Co.
Loma Linda University Medical Center
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