Stable liquid formulations of botulinum toxin

A - Human Necessities – 61 – K

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A61K 38/16 (2006.01) A61K 8/64 (2006.01) A61K 38/48 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2342243

The invention includes liquid formulations of botulinum toxin that are stable to storage in liquid form at standard refrigerator temperatures for at least 1- 2 years and to storage at higher temperatures for at least 6 months. The invention also includes methods of treatment using such formulations and uses of such formulations in the manufacture of medicaments for various therapeutic and cosmetic treatments.

L'invention concerne des formulations liquides de la toxine de botulinum présentant une stabilité de conservation sous forme liquide à des températures standard de réfrigération pendant au moins 1-2 ans et de conservation à des températures supérieures pendant au moins six mois. Elle concerne également des procédés de traitement mettant en application ces formulations et les utilisations de ces formulations pour la préparation de médicaments servant à différents traitements thérapeutiques et cosmétiques.

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