Stable, long acting salts of carboxamides for the treatment...

Details Stable, long acting salts of carboxamides for the treatment... Stable, long acting salts of carboxamides for the treatment...

C - Chemistry, Metallurgy

07

D

C07D 409/06 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) C07D 209/42 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 409/14 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2213361

Calcium, magnesium, lidocaine and benzathine salts of 2-oxindole-1-carboxamides of the formula (I): (see fig. I) (wherein X and Y are each H, halogen, alkyl, alkoxy, etc.; and R1 is an ester-forming group such as alkyl, etc.) are useful for the treatment of joint disease by intra-articular administration.

Sels calciques, magnésiens, lidocaïniques et benzathiniques de 2-oxindole-1-carboxamides de formule (I) : (voir fig. I) (où X et Y correspondent chacun à H, un halogène, un alkyle, un alcoxy, etc.; et R1 est un groupe formant un ester comme un groupe alkyle, etc.); ces composés sont utiles pour le traitement de la maladie articulaire par administration intra-articulaire.

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