Stable lozenge compositions providing rapid release of nicotine

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/20 (2006.01) A24B 15/14 (2006.01) A61K 31/465 (2006.01) A61K 47/38 (2006.01) A61P 25/34 (2006.01)

Patent

CA 2657932

Compositions comprising nicotine, which compositions provide a rapid release of nicotine. Nicotine is present in the form of a nicotine-cellulose combination. The compositions are designed for administration to the oral cavity where the nicotine is rapidly released from the composition and available for absorption through the oral mucosa. The compositions are lozenges and have excellent storage stability.

L'invention concerne des compositions à base de nicotine qui assurent une libération rapide de la nicotine. La nicotine est présente sous la forme d'une combinaison nicotine-cellulose. Les compositions sont conçues pour être administrées dans la cavité buccale où la nicotine est rapidement libérée par la composition et absorbée par la muqueuse buccale. Les compositions se présentent sous la forme de pastilles et possèdent une excellente stabilité au stockage.

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