Stable modifications of tegaserod hydrogen maleate

C - Chemistry – Metallurgy – 07 – D

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C07D 209/14 (2006.01) A61K 31/404 (2006.01)

Patent

CA 2532351

The present invention relates to crystalline forms of tegaserod hydrogen maleate, their use, in pharmaceutical compositions useful in the treatment of irritable bowel syndrome, gastro-esophageal reflux disease, functional dyspepsia, chronic constipation or diarrhea, and their production.

Cette invention se rapporte à des formes cristallines du maléate d'hydrogène tegaserod, à leur utilisation dans des compositions pharmaceutiques servant au traitement du syndrome du côlon irritable, du reflux gastrooesophagien pathologique, de la dyspepsie fonctionnelle, et de la constipation ou de la diarrhée chroniques, ainsi qu'à leur production.

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