A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/51 (2006.01) A61K 8/11 (2006.01) B01J 13/02 (2006.01)
Patent
CA 2646338
The invention is aimed at nanocapsule systems characterized in that they have high stability during long periods of time. These systems are useful for the controlled release of pharmacologically or cosmetically active ingredients of highly lipophilic nature. The system comprises nanocapsules with an average size less than 1 µm dispersed in an aqueous medium, wherein the nanocapsules have a structure which comprises a lipophilic phase containing a phospholipid component and one or more saturated and/or unsaturated C12-C24 chain fatty acids or derivatives thereof; and a hydrophilic phase which comprises chitosan or a derivative thereof and a polyoxyalkylenated compound.
La présente invention concerne des systèmes nanocapsulaires qui se caractérisent en ce qu'ils sont très stables sur de longues durées. Ces systèmes sont utiles pour la libération lente d'ingrédients fortement lipophiles actifs du point de vue pharmacologique ou cosmétique. Le système comprend des nanocapsules d'une taille moyenne inférieure à 1 µm dispersées dans un milieu aqueux, lesdites nanocapsules ayant une structure qui comprend une phase lipophile contenant un constituant phospholipide et un ou plusieurs acides gras à chaîne C12-C24 saturés ou non saturés ou dérivés de ces derniers et une phase hydrophile qui comprend du chitosane ou un dérivé de ce dernier et un composé polyoxyalkyléné.
Alonso Fernandez Ma Jose
Suarez Luque Silvia
Vila Pena Ana Isabel
Advanced In Vitro Cell Technologies S.l.
Advancell Advanced In Vitro Cell Technologies S.a.
Borden Ladner Gervais Llp
LandOfFree
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