Stable neural stem cell lines

Details Stable neural stem cell lines Stable neural stem cell lines

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) C12N 5/0793 (2010.01) C12N 5/0797 (2010.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) C12N 15/85 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2343571

A systematic and efficient method for establishing stable neural stem cell lines and neuronal progenitor lines is described. The resulting cell lines provide robust, simple, and reproducible cultures of human and other mammalian neurons in commercially useful mass quantities while maintaining normal karyotypes and normal neuronal phenotypes.

L'invention concerne une méthode systématique et efficace permettant d'établir des lignées de cellules embryonnaires neurales stables et des lignées souches neuronales. Les lignées de cellules obtenues produisent des cultures robustes, simples et reproductibles de neurones humains et d'autres mammifère. Ces cultures sont produites en masse, à des fins commerciales, tout en maintenant les caryotypes normaux et les phénotypes neuronaux normaux.

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