Stable, non-aqueous, single-phase gels and formulations...

Details Stable, non-aqueous, single-phase gels and formulations... Stable, non-aqueous, single-phase gels and formulations...

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 47/26 (2006.01) A61L 24/00 (2006.01)

Patent

CA 2508124

The present invention provides a suspension vehicle and suspension formulations deliverable from an implantable delivery device. In particular, the suspension vehicle of the present invention allows the formulation of beneficial agent suspensions that are stable over time at ambient and physiological temperatures. In addition, the beneficial agent suspensions formed using the suspension vehicle of the present invention allow controlled delivery of beneficial agent from an implanted delivery device over sustained periods of time, even when such delivery occurs at low flow rates, through a small-diameter delivery channel. Also included in the present invention are implantable delivery devices.

La présente invention concerne un support de suspension et des formulations en suspension pouvant être administrées à partir d'un dispositif d'administration implantable. Le support de suspension de la présente invention permet, en particulier, de formuler des suspensions d'agents bénéfiques stables dans la durée à température ambiante et physiologique. De plus, les suspensions d'agents bénéfiques formées à l'aide du support de suspension de la présente invention permettent de procéder à une administration contrôlée de l'agent bénéfique à partir d'un dispositif d'administration implanté sur des périodes de temps prolongées, y compris lorsqu'une telle administation se produit à faible débit, à travers un canal d'administration de diamètre réduit. La présente invention concerne également des dispositifs d'administration.

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