Stable non-aqueous single phase viscous vehicles and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/10 (2006.01) A61K 9/00 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/14 (2006.01) A61K 47/32 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2361424

This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1 x 101 reciprocal second.

L'invention a trait à des excipients visqueux à phase unique non aqueux stables et à des formulations utilisant ces excipients. Les formulations renferment au moins un agent utile en suspension uniforme dans l'excipient. La formulation peut être stockée à des températures comprises entre une température froide et une température corporelle pendant de longues périodes. Les formulations peuvent être administrées uniformément à l'aide de systèmes d'administration de médicament à une vitesse de cisaillement de sortie se situant entre environ 1 et 1 x 10<-7> seconde.

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