C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 229/22 (2006.01) A23L 1/305 (2006.01) A61K 31/205 (2006.01) C07C 59/285 (2006.01) C07C 227/42 (2006.01)
Patent
CA 2256712
Stable, non-hygroscopic salts of L(-)carnitine and alkanoyl L(-)carnitines with mucic acid of formula (I) are disclosed wherein the molar ratio between the carnitine moiety and mucic acid is 2:1. A process for producing the salts and solid orally administrable compositions containing same are also disclosed.
On décrit des sels non hygroscopiques de L(-)carnitine et de dérivés alcanoyles de L(-)carnitine avec de l'acide mucique, de la formule (I) dans lesquels le rapport molaire entre la fraction carnitine et l'acide mucique est de 2/1. On décrit également un procédé de production de ces sels ainsi que des compositions solides contenant ceux-ci et pouvant être administrées oralement.
Fassi Aldo
Kirby Eades Gale Baker
Sigma-Tau Industrie Farmaceutiche Riunite S.p.a.
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