A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 8/20 (2006.01) A61K 8/33 (2006.01) A61K 8/34 (2006.01) A61K 8/35 (2006.01) A61K 8/42 (2006.01) A61K 8/49 (2006.01) A61Q 11/00 (2006.01)
Patent
CA 2456341
Stable topical oral compositions comprising at least a minimally effective amount of chlorite ion are disclosed, wherein the pH of the final composition is greater than 7, the composition is essentially free of chlorine dioxide, and the composition is stable against loss of chlorite for a period of at least one year under normal storage conditions at about 25~C or for a period of 3 months under accelerated storage conditions at about 40 ~C. Preferably the compositions further comprise a flavor system, which is stable against degradation by chlorite. The compositions are formulated as therapeutic rinses, especially mouth rinses, as well as toothpastes, gels, tooth powders, chewing gums, mouth sprays, lozenges (including breath mints), dental implements (such as dental floss and tape), and pet care products.
La présente invention concerne des compositions buccales topiques stables comprenant au moins une quantité suffisante d'ions chlorite et dont le pH de la composition finale est supérieur à 7. Cette composition est par essence exempte de dioxyde de chlore. En outre, la composition est stable par rapport à la perte de chlorite sur une période d'au moins un an sous des conditions de stockage normales à une température d'environ 25 ·C ou sur une période de 3 mois dans des conditions de stockage accélérées à environ 40 ·C. La composition comporte de préférence un système aromatique stable par rapport à la dégradation par le chlorite. Ces compositions sont formulées comme produits de rinçage thérapeutiques, et plus particulièrement comme bains de bouches, ainsi que comme pâtes dentifrices, gels, poudres dentifrices, chewing-gums, spray buccal, pastilles, y-compris mentholées, accessoires d'hygiène dentaire tels que fil dentaire et bande dentaire, et produits d'hygiène vétérinaire.
Burgess Steven Carl
Clymer Paula Denise
Grimm James Carl
Johnson Christine Lula
Scott Douglas Craig
Ledgley Law
The Procter & Gamble Company
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