Stable oral pharmaceutical composition containing thyroid...

A - Human Necessities – 61 – K

Patent

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A61K 31/185 (2006.01) A61K 9/28 (2006.01) A61K 31/215 (2006.01) A61K 45/06 (2006.01) A61P 5/16 (2006.01)

Patent

CA 2642880

Compositions are described in which certain thyroid hormone receptor-binding compounds are formulated together with either an enteric coating, an antioxidant, or both an enteric coating and an antioxidant. Such formulation acts to prevent the formation of undesired reaction products in vivo.

L'invention concerne des compositions dans lesquelles certains composés se fixant aux récepteurs des hormones thyroïdiennes sont formulés avec soit un enrobage gastrorésistant, soit un antioxydant, soit à la fois un enrobage gastrorésistant et un antioxydant. Une telle formulation sert à empêcher la formation de produits de réaction non souhaités in vivo.

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