A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/475 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2695039
Stable pharmaceutical composition consisting of a hydrosoluble vinflunine salt and at least one diluent and one lubricant, said composition being in the form of a solid intended for oral administration. The hydrosoluble vinflunine salt is preferably Vinflunine ditartrate. The pharmaceutical composition is advantageously in the form of a capsule or tablet. The invention also concerns a method of treating cancer pathology comprising the oral administration of the pharmaceutical composition of the invention.
L'invention porte sur une composition pharmaceutique stable consistant en un sel de vinflunine hydrosoluble et en au moins un diluant et un lubrifiant, ladite composition étant sous la forme d'un solide destiné à une administration orale. Le sel de vinflunine hydrosoluble est, de préférence, le ditartrate de vinflunine. La composition pharmaceutique est avantageusement sous la forme d'une capsule ou d'un comprimé. L'invention porte également sur un procédé de traitement d'une pathologie cancéreuse, comprenant l'administration orale de la composition pharmaceutique de l'invention.
Avan Jean-Louis
Bougaret Joel
Paillard Bruno
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Pierre Fabre Medicament
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