Stable pharmaceutical composition for optimized delivery of...

A - Human Necessities – 61 – K

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A61K 31/496 (2006.01) A61K 31/00 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2735008

A pharmaceutical composition contains the compound 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1--yl)-1- [(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]- piperazine, and hydroxypropyl methyl cellulose (HPMC) having a viscosity of at least about 100 cP, wherein the composition does not contain any enzyme inhibitors.

L'invention porte sur une composition pharmaceutique qui contient le composé 1-benzoyl-4-[2-[4-méthoxy-7-(3-méthyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)méthyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoéthyl]-pipérazine, et de l'hydroxypropyl méthyl cellulose (HPMC) ayant une viscosité d'au moins environ 100 cP, la composition ne contenant pas d'inhibiteurs d'enzymes.

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