Stable pharmaceutical composition of a water-soluble...

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A61K 31/475 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2695040

A stable pharmaceutical composition comprising a water-soluble vinorelbine salt and at least one diluent and one lubricant, characterized in that it appears in a solid form intended for oral administration. The water soluble vinorelbine salt is advantageously vinorelbine ditartrate. The pharmaceutical composition advantageously appears as a gelatin capsule or tablet.

L'invention porte sur une composition pharmaceutique stable comprenant un sel de vinorelbine soluble dans l'eau et au moins un diluant et un lubrifiant, caractérisé par le fait qu'il apparaît sous une forme solide destiné à une administration orale. Le sel de vinorelbine soluble dans l'eau est avantageusement le ditartrate de vinorelbine. La composition pharmaceutique apparaît de manière avantageuse sous forme de capsule de gélatine ou de comprimé.

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