Stable pharmaceutical composition useful for treating...

A - Human Necessities – 61 – K

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A61K 33/24 (2006.01) A61K 9/00 (2006.01) A61K 9/10 (2006.01) A61K 31/60 (2006.01) A61P 1/00 (2006.01) A61K 47/36 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2474634

The present invention provides a pharmaceutical composition comprising at least one pharmaceutically acceptable bismuth-containing compound, at least one pharmaceutically acceptable non-clay-derived suspending agent, and water. The suspension exhibits reduced upward pH drift by comparison with an otherwise similar suspension which comprises a clay-derived suspending agent. Such compositions are useful in the prevention and treatment of gastrointestinal diseases and/or disorders.

L'invention porte sur une préparation pharmaceutique comprenant au moins un composé bismuthé, au moins un agent de suspension pharmacocompatible non dérivé de l'argile, et de l'eau. Cette suspension réduit la monté du pH par comparaison aux suspensions similaires contenant un agent de suspension dérivé de l'argile. Une telle préparation sert à prévenir et traiter les maladies et troubles gastro-intestinaux.

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