Stable reverse and multiple fluorocarbon emulsions

Details Stable reverse and multiple fluorocarbon emulsions Stable reverse and multiple fluorocarbon emulsions

A - Human Necessities

61

K

A61K 9/107 (2006.01) A61K 9/00 (2006.01) A61K 9/113 (2006.01)

Patent

CA 2191436

Stable reverse water-in-fluorocarbon emulsions and water-in-fluorocarbon-in-water multiple emulsions comprising the reverse fluorocarbon emulsions. The reverse emulsions comprise a continuous phase which is a highly fluorinated or perfluorinated compound, a discontinuous aqueous phase and a fluorinated surfactant or mixture of surfactants. The multiple emulsions comprise an aqueous continuous phase and a discontinuous phase comprising globules formed of aqueous droplets dispersed into a highly fluorinated or perfluorinated compound. The emulsions can contain pharmacologically active agents, and are particularly suitable for pulmonary drug delivery.

Ré-émulsions stables eau dans fluorocarbone et émulsions multiples eau dans fluorocarbone dans eau, comprenant ces ré-émulsions de fluorocarbone, lesquelles comportent une phase continue qui est un composé fortement fluoré ou perfluoré, une phase aqueuse discontinue, ainsi qu'un tensioactif fluoré ou un mélange de tensioactifs. Les émulsions multiples comportent une phase aqueuse continue ainsi qu'une phase aqueuse discontinue comprenant des globules formés de gouttelettes aqueuses dispersées dans un composé fortement fluoré ou perfluoré. Ces émulsions peuvent contenir des agents actifs sur le plan pharmacologique et elles trouvent une application particulière dans l'apport de médicaments aux poumons.

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