Stable salts of 5,10-methylenetetrahydrofolic acid

Details Stable salts of 5,10-methylenetetrahydrofolic acid Stable salts of 5,10-methylenetetrahydrofolic acid

C - Chemistry, Metallurgy

07

D

C07D 475/12 (2006.01) A61K 31/505 (2006.01) C07D 475/04 (2006.01)

Patent

CA 2078939

The invention relates to novel salts of 5,10-methylene-(6R)-, (6R,S)- and (6S)-tetrahydrofolic acid with sulfuric acid or a sulfonic acid, which are stable in solid form, to processes for the preparation of these salts and to their use as a constituent and/or as a starting material for the production of medicaments.

L'invention porte sur de nouveaux sels de l'acide 5,10-méthylène-(6R)-, (6R,S)- et (6S)-tétrahydrofolique avec de l'acide sulfurique ou sulfonique - lesquels sont stables sous leur forme solide -, et à des méthodes pour la préparation de ces sels et leur emploi comme constituants de médicaments et (ou) comme produits de départ pour leur production.

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