Stable solvates of avermectin compounds

Details Stable solvates of avermectin compounds Stable solvates of avermectin compounds

C - Chemistry, Metallurgy

07

H

C07H 19/01 (2006.01) A01N 43/80 (2006.01) A61K 31/70 (2006.01) C07D 493/22 (2006.01)

Patent

CA 2171871

There is disclosed a novel form of avermectin compounds wherein the avermectin compounds are crystallized as alcohol solvates to greatly enhance stability of the avermectin drug during long-term storage. The avermectin compounds have utility as highly potent antiparasitic, insecticidal, and anthelmintic agents and compositions for that use are also disclosed.

L'invention concerne une nouvelle forme de composés d'avermectine. Les composés d'avermectine sont cristallisés en solvates d'alcool afin d'accroître fortement la stabilité de l'avermectine en tant que médicament pour des stockages de longue durée. Les composés d'avermectine présentent une grande utilité en raison de leur pouvoir élevé en tant qu'antiparasites, insecticides et agents anthelminthiques. L'invention concerne également des compositions destinées à cet usage.

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