Stable tablet containing 4,5-epoxymorphinan derivative

Details Stable tablet containing 4,5-epoxymorphinan derivative Stable tablet containing 4,5-epoxymorphinan derivative

A - Human Necessities

61

K

A61K 31/485 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 47/02 (2006.01) A61K 47/26 (2006.01) A61K 47/32 (2006.01) A61K 47/36 (2006.01) A61P 17/04 (2006.01)

Patent

CA 2740476

The present invention relates to a stable tablet comprising a 4,5- epoxymorphinan derivative or a pharmacologically acceptable acid addition salt thereof as an effective ingredient. That is, the tablet according to the present invention comprises: (1) as the effective ingredient, a specific 4,5- epoxymorphinan derivative or a pharmacologically acceptable acid addition salt; (2) sodium thiosulfate; (3) at least one selected from the group consisting of saccharides and sugar alcohols; and (4) crospovidone, sodium carboxymethyl starch or a mixture thereof, in which tablet the content of the aforementioned (4) is 1 to 20% by weight per unit weight containing the aforementioned effective ingredient.

La présente invention concerne un comprimé stable contenant un dérivé de 4,5-époxymorphinane ou lun de ses sels daddition dacide pharmacologiquement permissibles en tant que principe actif. De manière spécifique, ce comprimé contient (1) en tant que principe actif, un dérivé prescrit de 4,5-époxymorphinane ou lun de ses sels daddition dacide pharmacologiquement permissibles; (2) du thiosulfate de sodium; (3) au moins un sucre ou un alcool de sucre choisi dans un groupe composé de sucres et dalcools de sucre; et (4) de la crospovidone, de lamidon carboxyméthylique sodique, ou un mélange de ces substances; où la quantité du composant (4) susmentionné incluse est de 1 à 20 % en poids par poids unitaire de principe actif contenu susmentionné.

Affiliated with

Also associated with

Rating

Stable tablet containing 4,5-epoxymorphinan derivative does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Stable tablet containing 4,5-epoxymorphinan derivative, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stable tablet containing 4,5-epoxymorphinan derivative will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1441362