Stable tablet containing droxidopa

Details Stable tablet containing droxidopa Stable tablet containing droxidopa

A - Human Necessities

61

K

A61K 31/198 (2006.01) A61K 9/20 (2006.01) A61K 47/10 (2006.01) A61K 47/26 (2006.01) A61K 47/32 (2006.01) A61K 47/36 (2006.01) A61K 47/38 (2006.01) A61P 9/00 (2006.01) A61P 25/16 (2006.01)

Patent

CA 2608690

It is intended to provide a tablet containing droxidopa as an active ingredient in an amount of 20 to 80% by weight of the total weight of the tablet characterized by containing at least one excipient selected from mannitol, lactose, erythritol, glucose, sucrose, crystalline cellulose and starch derived from corn. It is further intended to provide a stable tablet containing droxidopa as an active ingredient, which is a preparation or the like containing modified starch derived from corn or polyvinyl alcohol as a binder.

La présente invention concerne un comprimé contenant de la droxidopa au titre de principe actif à une teneur comprise entre 20 et 80 % en masse de la masse totale du comprimé, et caractérisé en ce qu'il contient au moins un excipient sélectionné parmi le mannitol, le lactose, l'érythritol, le glucose, le sucrose, la cellulose cristalline et l'amidon de maïs. La présente invention concerne en outre un comprimé stable comprenant de la droxidopa au titre de principe actif, qui est une préparation ou une substance similaire contenant de l'amidon modifié de maïs ou un alcool polyvinylique au titre d'agent liant.

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