Stable topical formulations with good active ingredient...

Details Stable topical formulations with good active ingredient... Stable topical formulations with good active ingredient...

A - Human Necessities

61

K

A61K 47/00 (2006.01) A61K 9/06 (2006.01) A61K 31/70 (2006.01) A61K 47/12 (2006.01) A61K 47/20 (2006.01) A61K 47/28 (2006.01) C07H 17/08 (2006.01) A61K 31/71 (1995.01)

Patent

CA 2107620

A stable topical formulation with good active ingredient release characteristics, comprising at least one macrolide antibiotic which is lipophilized with at least one former of oppositely charged ions which is selected from the group consisting of alkyl sulfates, alkylsulfonates, and alkyl salicylates, RX, where R represents a linear and/or branched alkyl group with 6-32 C atoms, and X represents a sulfate, sulfonate, or salicylate group.

Formulation topique stable, possédant de bonnes caractéristiques de libération d'ingrédients actifs. Elle renferme au moins un macrolide antibiotique - lipophilisé avec au moins une source d'ions opposés, choisie parmi des sulfates d'alkyle, des sulfonates alkyliques et des salicylates d'alkyle - et RX, où R représente un groupe alkyle linéaire et (ou) ramifié, de 6 à 32 atomes de C, X étant un groupe sulfate, sulfonate ou salicylate.

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