Stable topiramate formulations

Details Stable topiramate formulations Stable topiramate formulations

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 9/24 (2006.01) A61K 9/50 (2006.01) A61K 31/135 (2006.01) A61K 31/35 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2503147

Bi- or multi-phasic tablets comprising an effective amount of a moisture sensitive active ingredient, which in particular is topiramate, wherein at least one of the phases comprises hygroscopic gum material, which preferably is xanthan gum, and wherein none of the phases contains both moisture sensitive active ingredient and hygroscopic gum material.

L'invention concerne des comprimés biphasiques ou multiphasiques comprenant une quantité efficace d'un ingrédient actif sensible à l'humidité, en particulier du topiramate, au moins une des phases comprenant de la gomme hygroscopique, de préférence de la gomme de xanthane, mais aucune des phases ne contenant à la fois l'ingrédient actif sensible à l'humidité et la gomme hygroscopique.

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