Stably transfected cell lines expressing gaba-a receptors

Details Stably transfected cell lines expressing gaba-a receptors Stably transfected cell lines expressing gaba-a receptors

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01) C07K 17/02 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2151236

The present invention relates to a stably co-transfected eukaryotic cell line capable of expressing a human GABA A receptor, which receptor comprises the .alpha.1.beta.3.gamma.2, .alpha.2.beta.3.gamma.2, .alpha.5.beta.3.gamma.2, .alpha.1.beta.1.gamma.2, .alpha.1.beta.2.gamma.2, .alpha.3.beta.3.gamma.2 or .alpha.6.beta.3.gamma.2 subunit combination; to membrane preparations derived from cultures thereof; and to the use of the cell line in designing and developing GABA A receptor subtype-selective medicaments.

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