C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 48/00 (2006.01) C07K 14/00 (2006.01) C07K 14/31 (2006.01) C12N 1/20 (2006.01) C12N 15/63 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2323724
The present invention relates to 11 novel genes from S. aureus and the polypeptides they encode. Also provided are vectors, host cells, antibodies and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of S. aureus polypeptide activity. The invention additionally relates to diagnostic methods for detecting Staphylococcus nucleic acids, polypeptides and antibodies in a biological sample. The present invention further relates to novel vaccines for the prevention or attenuation of infection by Staphylococcus.
La présente invention concerne 11 gènes issus du staphylocoque doré et les polypeptides qu'ils codent. L'invention concerne également des vecteurs, ces cellules hôtes, des anticorps et des procédés à recombinaison permettant de les obtenir. L'invention concerne aussi des techniques de recherche systématique permettant d'identifier des agonistes et des antagonistes de l'activité polypeptide du staphylocoque doré. L'invention concerne en outre des techniques de diagnostic permettant de détecter dans un échantillon biologique des acides nucléiques, des polypeptides et des anticorps du staphylocoque doré. L'invention concerne enfin des vaccins permettant la prévention ou l'atténuation de l'infection par le staphylocoque.
Choi Gil H.
Simpson Andrew J. G.
Human Genome Sciences Inc.
Ludwig Institute For Cancer Research
Mbm Intellectual Property Law Llp
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