A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/40 (2006.01) A61K 31/7088 (2006.01) A61K 39/085 (2006.01) A61K 39/395 (2006.01) A61P 31/04 (2006.01) C12Q 1/14 (2006.01) C12Q 1/18 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2581746
Iron-regulated surface determinant proteins IsdA, IsdB and IsdC from Staphylococcus aureus, as well as antibodies, antisense nucleic acids and siRNA specific to IsdA, IsdB or IsdC are used as vaccines and in method for treating or preventing a disease or condition associated with S. aureus infections Screening assays for identifying agents that inhibit or interfere with the expression level and/or function of IsdA, IsdB or IsdC are also described.
L'invention concerne des nouveaux anti-infectieux qui agissent sur des gènes Isd ("iron-regulated surface determinants") de Staphylococcus aureus (S. aureus), IsdA, IsdB, et IsdC.
Heinrichs David E.
Vermeiren Christie
Riches Mckenzie & Herbert Llp
The University Of Western Ontario
LandOfFree
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