Stat3 phosphorylation inhibitor and notch1 expression inhibitor

Details Stat3 phosphorylation inhibitor and notch1 expression inhibitor Stat3 phosphorylation inhibitor and notch1 expression inhibitor

A - Human Necessities

61

K

A61K 31/122 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2583699

A STAT3 phosphorylation inhibitor and Notch1 expression inhibitor each comprising as an active ingredient a compound of the formula: (1) wherein each of R1, R2 and R3 is a hydrogen atom or a methyl group, and X is a C10-C28 linear or branched alkyl, alkylene or alkenylene group.

La présente invention a pour objet un inhibiteur de phosphorylation de STAT3 et un inhibiteur d'expression de Notch1, chacun incluant au titre de principe actif un composé de formule: (1) où chacun des groupements R1, R2 et R3 est un atome d'hydrogène ou un groupement méthyle, et X est un groupement alkyle, alkylène ou alcénylène linéaire ou ramifié en C10-C28.

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