Statin and omega-3 fatty acids for reduction of apo-b levels

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/366 (2006.01) A61K 31/202 (2006.01) A61K 31/22 (2006.01) A61K 31/40 (2006.01) A61K 31/405 (2006.01) A61K 31/47 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2672931

Methods of utilizing a combined administration or a unit dosage of a combination of an HMG-CoA inhibitor and omega-3 fatty acids for the reduction of apolipoprotein-B levels. The methods are especially useful in the treatment of- patients with hypertriglyceridemia or hypercholesterolemia or mixed dyslipidemia, coronary heart disease (CHD), vascular disease, atherosclerotic disease and related conditions, and for the prevention or reduction of cardiovascular, cardiac, and vascular events.

L'invention concerne des procédés d'utilisation d'une administration combinée ou d'une unité posologique d'une combinaison d'un inhibiteur de HMG-CoA et d'acides gras oméga-3 pour la réduction des niveaux d'apolipoprotéine B. Les procédés sont particulièrement utiles pour le traitement de patients présentant une hypertriglycéridémie ou une hypercholestérolémie ou une dyslipidémie mixte, une coronaropathie (CHD), une maladie vasculaire, une maladie athérosclérotique ou des troubles associés, et pour la prévention ou la réduction des événements cardiovasculaires, cardiaques et vasculaires.

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