Stationary phases and a purification process using the...

A - Human Necessities – 61 – K

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A61K 38/00 (2006.01) C07K 7/00 (2006.01)

Patent

CA 2537574

This invention relates to a novel stationary phase of Formula I and a method for purifying a peptide or lipopeptide in liquid chromatography using select stationary phases, including the stationary phases of Formula I to improve the resolution and/or productivity of the purification. This chromatographic method can be used for either an analytical or preparative scale purification.

L'invention concerne une nouvelle phase stationnaire de formule I, ainsi qu'un procédé de purification d'un peptide ou d'un lipopeptide dans une chromatographie liquide, au moyen de phases stationnaires choisies, notamment les phases stationnaires de formule I selon l'invention. Ces phases permettent d'améliorer la résolution et/ou la productivité de la purification. Ce procédé chromatographique peut être mis en oeuvre dans la purification analytique ou dans la purification à l'échelle préparative.

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